Next comes the question, precisely how doesthe order of the A , B , C , D units determine the arrangement of the amino acids in the protein? Thisis the central unsolved problem in biology today. The first clues, or pieces ofinformation, however, are these: There are in the cell tiny particles called ribosomes,and it is now known that that is the place where proteins are made. But the ribosomesare not in the nucleus, where the DNA and its instructions are. Something seemsto be the matter. However, it is also known that little molecule pieces comeoff the DNA—not as long as the big DNA molecule that carries all the informationitself, but like a small section of it. This is called RNA, but that is notessential. It is a kind of copy of the DNA, a short copy. The RNA, whichsomehow carries a message as to what kind of protein to make goes over to theribosome; that is known. When it gets there, protein is synthesized at theribosome. That is also known. However, the details of how the amino acids comein and are arranged in accordance with a code that is on the RNA are, as yet,still unknown. We do not know how to read it. If we knew, for example, the “lineup”A , B , C , C , A , we could not tell you what protein is to be made.
下面问题来了,就是A、B、C、D单元的顺序,是如何精确地规定蛋白质中的氨基酸的排列的?这是今天生物学中,尚未解决的中心问题。然而,第一条线索、或信息片段,是这些:在细胞中,有小的粒子,被称为核糖体,现在知道,蛋白质就是在这里制造的。但是,核糖体并不在细胞核中,而DNA和及其指示,则在其中。似乎应该有某物,在起作用。然而,现在我们知道的是,有小的分子片,会从DNA中出来;大的DNA分子,承载着所有信息,这些小片,没有大的DNA那么长,而是一些小的片段,他们被称为RNA,但这还不是根本的。它是DNA的某种拷贝,一个短的拷贝。RNA以某种方式带着一条消息,朝着核糖体走去,该消息,是关于制造哪种蛋白质的;这是知道的。当RNA到达核糖体时,蛋白质就被合成。这也是知道的。然而,氨基酸是如何进来的,以及是如何依据RNA中的指令而被排列的,这些细节,还不知道。我们不知道,如何读它{RNA}。如果我们知道的话,例如,知道A , B , C , C , A这一“阵容”,但我们不能告诉你,哪种蛋白质,将被制造。
下面问题来了,就是A、B、C、D单元的顺序,是如何精确地规定蛋白质中的氨基酸的排列的?这是今天生物学中,尚未解决的中心问题。然而,第一条线索、或信息片段,是这些:在细胞中,有小的粒子,被称为核糖体,现在知道,蛋白质就是在这里制造的。但是,核糖体并不在细胞核中,而DNA和及其指示,则在其中。似乎应该有某物,在起作用。然而,现在我们知道的是,有小的分子片,会从DNA中出来;大的DNA分子,承载着所有信息,这些小片,没有大的DNA那么长,而是一些小的片段,他们被称为RNA,但这还不是根本的。它是DNA的某种拷贝,一个短的拷贝。RNA以某种方式带着一条消息,朝着核糖体走去,该消息,是关于制造哪种蛋白质的;这是知道的。当RNA到达核糖体时,蛋白质就被合成。这也是知道的。然而,氨基酸是如何进来的,以及是如何依据RNA中的指令而被排列的,这些细节,还不知道。我们不知道,如何读它{RNA}。如果我们知道的话,例如,知道A , B , C , C , A这一“阵容”,但我们不能告诉你,哪种蛋白质,将被制造。










