在豆瓣看到的 觉得挺好玩的~~~我的是什么呢...
Abstract The Morris water maze (MWM) was described 20 years ago as a device to investigate spatial learning and memory in laboratory rats.In the meanwhile, it has become one of the most frequently used laboratory tools in behavioral neuroscience. Many methodologicalvariations of the MWM task have been and are being used by research groups in many different applications. However, researchers havebecome increasingly aware that MWM performance is influenced by factors such as apparatus or training procedure as well as by thecharacteristics of the experimental animals (sex, species / strain, age, nutritional state, exposure to stress or infection). Lesions in distinctbrain regions like hippocampus, striatum, basal forebrain, cerebellum and cerebral cortex were shown to impair MWM performance, butdisconnecting rather than destroying brain regions relevant for spatial learning may impair MWM performance as well. Spatial learning ingeneral and MWM performance in particular appear to depend upon the coordinated action of different brain regions and neurotransmittersystems constituting a functionally integrated neural network. Finally, the MWM task has often been used in the validation of rodentmodels for neurocognitive disorders and the evaluation of possible neurocognitive treatments. Through its many applications, MWMtesting gained a position at the very core of contemporary neuroscience research. Ó 2001 Elsevier Science B.V. All rights reserved.
好吧 我其实是想翻译这一段...
期待大家的答案~~
Abstract The Morris water maze (MWM) was described 20 years ago as a device to investigate spatial learning and memory in laboratory rats.In the meanwhile, it has become one of the most frequently used laboratory tools in behavioral neuroscience. Many methodologicalvariations of the MWM task have been and are being used by research groups in many different applications. However, researchers havebecome increasingly aware that MWM performance is influenced by factors such as apparatus or training procedure as well as by thecharacteristics of the experimental animals (sex, species / strain, age, nutritional state, exposure to stress or infection). Lesions in distinctbrain regions like hippocampus, striatum, basal forebrain, cerebellum and cerebral cortex were shown to impair MWM performance, butdisconnecting rather than destroying brain regions relevant for spatial learning may impair MWM performance as well. Spatial learning ingeneral and MWM performance in particular appear to depend upon the coordinated action of different brain regions and neurotransmittersystems constituting a functionally integrated neural network. Finally, the MWM task has often been used in the validation of rodentmodels for neurocognitive disorders and the evaluation of possible neurocognitive treatments. Through its many applications, MWMtesting gained a position at the very core of contemporary neuroscience research. Ó 2001 Elsevier Science B.V. All rights reserved.
好吧 我其实是想翻译这一段...
期待大家的答案~~
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